Dear Authors,
If you believe that your paper was mistakenly rejected by other leading journals and you do not agree with final decision, the editors of Reports of Practical Oncology and Radiotherapy offer new fast track review. You may submit your manuscript to Reports of Practical Oncology and Radiotherapy together with all prior peer-reviews obtained from the other journal and your rebuttal letter. We guarantee review based decision within 72 hours from the time we will receive your manuscript.

Fast track submission process: Please submit the manuscript with all reviews and rebuttal letter by email to Dr. Michal Masternak ( for fast review processing. To assure immediate attention the email title must to include: RPOR-fast track- Last Name First Name (of corresponding author).

Volume 5, Number 4, 2000

Palliative HDR brachytherapy in treatment of advanced esophageal cancer

Skowronek J, Adamska K, Suwalska M, Zwierzchowski G.


Introduction: Patients not qualified for surgery due to the location and clinically advanced stage of oesophageal cancer constitute a group with poor prognosis. Only few of them qualify for radical teletherapy, most of them are being treated symptomatically. The paper presents preliminary results of HDR brachytherapy applied in patients with inoperable oesophageal cancer.
Material and Methods: Between May 1999 and February 2000, 37 patients with inoperable oesophageal cancer were treated by HDR brachytherapy. The patients´ age ranged between 42 and 81 years, mean: 53.1 yr. In HDR brachytherapy the most commonly employed dose was that of 21.5 Gy (in three fractions) at the tumour site. In four cases the mediastinum was additionally irradiated with a dose of 20 Gy in five fractions, and in nine patients treated radically, teletherapy with a dose of 50-60 Gy at the vicinity of the oesophagus was used following brachytherapy. The effect of the treatment in the form of local remission and regression of dysphagia was assessed in the 1st, 3rd and 6th month of follow-up after the completion of the treatment.
Results: The mean follow-up was 6 months. Total remission, partial remission and no remission, as assessed in the 1st month after the treatment, was found in 7 (18.9%), 18 (48.6%), and 12 (32.4%) patients, respectively. After the 3- and 6-month follow-up remission was re-affirmed in two-thirds of the patients under observation. In the group of patients treated with the combination method total remission was found in two (20%) patients, whereas partial remission was ascertained in 6 (60%) patients. In four (10.8%) patients oesophageal fistula was detected during the follow-up period.
Conclusions: HDR brachytherapy was found to lead to regression of dysfagia in a significant number of patients with inoperable oesophageal cancer. In some patients total remission was achieved lasting more than six months. Tolerance for the treatment was good, and the number of complications did not differ from that reported by other authors.

Signature: Rep Pract Oncol Radiother, 2000; 5(4) : 111-119

« back


Indexed in: EMBASE®, the Excerpta Medica database, the Elsevier BIOBASE (Current Awareness in Biological Sciences) and in the Index Copernicus.