Dear Authors,
If you believe that your paper was mistakenly rejected by other leading journals and you do not agree with final decision, the editors of Reports of Practical Oncology and Radiotherapy offer new fast track review. You may submit your manuscript to Reports of Practical Oncology and Radiotherapy together with all prior peer-reviews obtained from the other journal and your rebuttal letter. We guarantee review based decision within 72 hours from the time we will receive your manuscript.

Fast track submission process: Please submit the manuscript with all reviews and rebuttal letter by email to Dr. Michal Masternak (michal.masternak@ucf.edu) for fast review processing. To assure immediate attention the email title must to include: RPOR-fast track- Last Name First Name (of corresponding author).

Volume 23, Number 3, 2018

CyberKnife Stereotactic Radiosurgery in brain metastases: A report from Latin America with literature review

Cuauhtémoc de la Peña, Jorge H. Guajardo, María F. Gonzalez, César González, Benjamín Cruz

Summary:

Background and aim Stereotactic radiosurgery is increasingly being employed for the treatment of brain metastases, both as an adjuvant to surgical resection, and also as a primary treatment modality. The aim of this study is to evaluate overall survival and local control in patients with brain metastases treated with CyberKnife Stereotactic Radiosurgery (CKRS), due to the lack of evidence reported in Latin America. Materials and methods We performed a retrospective chart review from October 2011 to January 2017 of 49 patients with 152 brain metastases. Clinical and prognostic factors were further analyzed by independent analysis. Kaplan–Meier curves were constructed for overall survival and local control. The median follow-up period was 12 months (range, 1–37 months). Results The median age was 61 years (range, 27–85 years) and Karnofsky performance status >70 in 96% of the patients. The median overall survival rate was 15.5 months (95% confidence interval [CI], 10.23–24.3 months). Overall 3-month, 6-month and 1-year local control rates were 98% (95% CI, 85–99%), 96% (95% CI, 82–99%), and 90% (94% IC, 76–96%), respectively. Local failure (LF) was observed in 6 patients (18 lesions). No late complications, such as radiation necrosis, were observed during the follow-up period. Conclusions CKRS achieves excellent overall survival and local control rates with low toxicity in patients with brain metastases.

Signature: Rep Pract Oncol Radiother, 2018; 23(3) : 161-167


« back

 
INDEXED IN:

Indexed in: EMBASE®, the Excerpta Medica database, the Elsevier BIOBASE (Current Awareness in Biological Sciences) and in the Index Copernicus.

http://www.sciencedirect.com/science/journal/15071367/19/2